Electrochemical potential in organic chemistry has to do with the balance and equilibrium of a given element in a given space, relative to its membrane, to arrive at its electrochemical potential. Or, energy per Mole. (Mole is a scientific unit of measure)
In electronics it is the migration of ions, decay of electrodes, or across a given medium, the voltage/charge that determines the electrochemical potential. Or energy per charge.
Completely different meanings for electrochemical potential. The organic mechanisms of these are well established, using similar ideas and nomenclatures as used in electronics. So, cross translations even for technical people are always going to be problematic. The Michaelis-Menten model is the accepted theory in biochemistry. Think of the ATP synthase as a three cylinder rotary engine. Each sequential firing of a cylinder is a state, or chemical condition. As we add electron flow to this we add fuel to this mechanism.
ATP is the most common means or type of cell energy in the body, and is made in the Mitochondrion of the cell. In humans there are 30 or so types of ATP, and these can be added to or subtracted from the treatment area. ATP (Adenosine Triphosphate) is an enzyme, produced in the cell by (oxidative phosphorylization) adding a phosphorus molecule to a subunit of ADP (Adenosine Diphosphate). ATP then is also the product of a cyclic enzyme catalysis that is theoretically accelerated during and as a result of Rife therapy. Reflected immediately by changes in pH, and in the useful, or the apparent vitality.
See: JWLABS : Pentagon release: ECC 1989 model (electro-conformational coupling; theoretical model in enzyme kinetics) Presumably, any muscle tissue of the body will produce at least some ATP of one type or another. More is produced by the denser muscles, and the most productive of ATP is probably the heart muscle.
ATP is stimulated by adding current energy at frequency across the electron transport chain, creating a faster proton motive force to synthesize ATP at a higher rate per mol per second than normal. The result is that a proton gradient occurs and the cycle evidently becomes rapidly exhausted, then chemically begins to reverse. By direct observers reports, commonly we can see that continued therapy accelerates this reverse side of the cycle, and in a short time, no cyclic changes are observed.
This is probably a biological state of electrochemical equilibrium. In this regard, most new users will show either activity on one of the two sides of this cycle, usually reflected in pH. Generally speaking, if the cycle adds ATP, pH will go up, and the user will experience an increase in strength and stamina. On the reverse side of the cycle, ATP will reduce, pH will drop, and the user will experience fatigue, toxicity and in some instances, symptomatic instability.
Which direction the cycle takes is probably determined entirely by the direction already in progress, and the introduction of Rife Therapy merely accelerates either side, until it is completed and the cycles repeat. The user who was fatigued by the therapy in the beginners stages, began therapy on the reverse side of the cycle, may experience the opposite up-cycle, some time later in their progress with the therapy. In both cases, the most profound observable changes of this kind generally do not persist once equilibrium is achieved.
In Rife Therapy we would call it maintenance level.
It is further reasonable to assume that many of the known voltage gated ion channels, the calcium ion channel, the potassium channel, sodium channel, proton channel, etc, might be excited and accelerated or inhibited and locked. A broad potential cascade of electrochemical changes in the body that may occur during the therapy. Nevertheless, it appears that the same cycling effects as detailed in ATP synthase, are present in each voltage gated ion channel, the end result of which is apparently voltage induced electrochemical equilibrium. This may also provide a more plausible theory to explain how therapies that clearly call for a certain polarity according to common logic, are still changed for the better using the opposite polarity, and often equally well.
If changing polarity does not change the cyclic reaction, as we have seen in ATP synthase, the enzyme wheel rotates clockwise, whether it is storing energy or expending it. Logic suggests this physiological state of equilibrium lowers the electrochemical potential but also provides a full spectrum of enzyme catalytic reactions, broad enough to over ride many of the expected effects of simple electro-stimulation of an area. For example hyper thyroid is treated the same as hypothyroid, but with more emphasis on the anion channel rather than the cation channel. Either way, the cycles appear to repeat every few days and rarely more than once or twice. It would appear that time away from Rife Therapy, tends to give any affected voltage gated cyclic reactions time to reset themselves. The time it takes for the electrochemical potential to increase again is not established.
The importance of reset time is also not established, however, it appears that in some cases it is of great importance to maintain equilibrium until pH is under control. The same case may later require repeated resetting for best results.